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Dr. LEUNG Ching Yu, Roland

MB ChB (Edin), MRCP (London), DABIM (Onc)

Honorary Clinical Associate Professor in Medical Oncology           

University Department of Medicine

Li Ka Shing Faculty of Medicine

The University of Hong Kong

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Biography

I am a medical oncologist trained in the US at New York University Medical Center and Memorial Sloan Kettering Cancer Center. My main interest is the exploration of predictive bio-markers in the clinical treatment of cancer. With the explosion of molecular targeted therapies with specific target of action, it is imperative that we as oncologists have access to technology which can predict which patients will benefit most from these treatment and not expose patients to empirical treatment. Since returning to Hong Kong 10 years ago, I focus on breast cancer, adenocarcinoma of lung, neuroendocrine tumuors and tumours with targetable genetic aberrations like melanoma, some GI cancers, GISTs and a subset of sarcomas. Currently I am an associate consultant in the Department of Medicine, Queen Mary Hospital and honorary assistant professor in Department of Medicine, University of Hong Kong.

Five Most Representative Publications

1) Lin CH, Yap YS, Lee KH, Im SA, Naito Y, Yeo W, Ueno T, Kwong A, Li H, Huang SM, Leung R, Han W, Tan B, Hu FC, Huang CS, Cheng AL, Lu YS; Asian Breast Cancer Cooperative Group.
Contrasting Epidemiology and Clinicopathology of Female Breast Cancer in Asians vs the US Population.

J Natl Cancer Inst. 2019 Dec 1;111(12):1298-1306. doi: 10.1093/jnci/djz090.PMID: 31093668 

[Citation: 31 ] [IF: 13.76 (JCR 2011)]

2) Chiu JW, Leung R, Tang V, Cheuk WY, Lo J, Kwok GW, Wong H, Suen D, Cheung P, Wong TT, Yau T, Kwong A.
Changing pattern of recurrences in patients with early HER2-positive breast cancer receiving neoadjuvant chemotherapy in the era of dual anti-HER2 therapy.
Postgrad Med J 2019; 95(1121):155-161.

[Citation: 1 ] [IF: 1.91 (JCR 2019)]

3)  Roland C Y Leung , Thomas C C Yau , Miranda C M Chan , Sharon W W Chan , Terence W C Chan , Yvonne Y Y Tsang , Ting Ting Wong , Calvin Chao , Carl Yoshizawa , Inda S Soong , Wing-Hong Kwan , Carol C H Kwok , Joyce S J Suen , Roger K C Ngan , Polly S Y Cheung                                              

 The Impact of the Oncotype DX Breast Cancer Assay on Treatment Decisions for Women With Estrogen Receptor-Positive, Node-Negative Breast Carcinoma in Hong Kong

Clin Breast Cancer. 2016 Oct;16(5):372-378 doi: 10.1016/j.clbc.2016.03.002. Epub 2016 Mar 17.
[Citation: 14 ] [IF: 2.82 (JCR 2016)]

4)  Roland Leung , Brian Lang, Hilda Wong, Joanne Chiu, Wan K Yat, Tony Shek, Woo Y Cho, Lo C Yau, Thomas Yau

Advances in the systemic treatment of neuroendocrine tumors in the era of molecular therapy

Anticancer Agents Med Chem. 2013 Mar;13(3):382-8.

[Citation: 14 ] [IF: 2.60 (JCR 2016)]

5)  Renat Shaykhiev 1, Rui Wang, Rachel K Zwick, Neil R Hackett, Roland Leung, Malcolm A S Moore, Camelia S Sima, Ion Wa Chao, Robert J Downey, Yael Strulovici-Barel, Jacqueline Salit, Ronald G Crystal

Airway basal cells of healthy smokers express an embryonic stem cell signature relevant to lung cancer

Stem Cells. 2013 Sep;31(9):1992-2002. doi: 10.1002/stem.1459.

[Citation: 25 ] [IF: 5.60 (JCR 2016)]

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